Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

Read More

Overview

Feature Articles

Latest Lupus News and Research

Long-term side effects of modern treatment for rheumatoid arthritis

Long-term side effects of modern treatment for rheumatoid arthritis

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

Breaking barriers to improve access to quality information about lupus

Breaking barriers to improve access to quality information about lupus

Burden of autoimmune disease continues to increase over time, research suggests

Burden of autoimmune disease continues to increase over time, research suggests

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Pawsitive test: Dogs sniff out COVID-19 with high accuracy, study shows

Pawsitive test: Dogs sniff out COVID-19 with high accuracy, study shows

Lupus Landmark Study launched to accelerate the development of personalized treatments for lupus patients

Lupus Landmark Study launched to accelerate the development of personalized treatments for lupus patients

Long-term opioid use more common among patients with rheumatic and musculoskeletal conditions

Long-term opioid use more common among patients with rheumatic and musculoskeletal conditions

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

High-fat diets can promote atherosclerosis via gut bacteria interactions with the immune system

High-fat diets can promote atherosclerosis via gut bacteria interactions with the immune system

Understanding Lupus: an interview with the Garvan Institute

Understanding Lupus: an interview with the Garvan Institute

Cancer-fighting immune cells can fuel their ability to attack tumors

Cancer-fighting immune cells can fuel their ability to attack tumors

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

US adults with post-COVID-19 condition more likely to face healthcare access and affordability challenges

US adults with post-COVID-19 condition more likely to face healthcare access and affordability challenges

New clinical RNA sequencing platform helps carve a path for Precision Child Health

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Current CVD risk assessments fall short for women from diverse racial and ethnic backgrounds

Current CVD risk assessments fall short for women from diverse racial and ethnic backgrounds

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

Study indicates interspecies transmission of SARS-CoV-2 between humans and their pets occurs regularly

How do viral infections cause autoimmune diseases?

How do viral infections cause autoimmune diseases?