Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Researchers from Children's Hospital of Philadelphia (CHOP) recently discovered that extremely thorough "deep sequencing" of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods.

1 Jun 2023

CardioGen upgrade facilitates more accurate diagnosis of monogenic cardiovascular diseases

Over 2,800 cases, representing a 31% increase, added to BGI Genomics-led CardioGen's hereditary cardiovascular disease gene data.

From BGI Genomics 1 Jun 2023

Researchers create an open-source, reproducible analysis platform for pediatric brain tumors

Researchers from Children's Hospital of Philadelphia, the Alex's Lemonade Stand Foundation Childhood Cancer Data Lab, the Children's Brain Tumor Network, the Pacific Pediatric Neuro-Oncology Consortium, and more than 20 additional institutions have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors.

31 May 2023

Computational approach could help pinpoint causal variants in the noncoding genome

Less than two percent of the human genome codes for proteins, with the rest being noncoding and likely helping with gene regulation.

30 May 2023

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

A scientific collaboration between the University of São Paulo (USP) in Ribeirão Preto, Brazil, and Clemente Estable Institute of Biological Research (IIBCE) in Montevideo, Uruguay, is experimenting with two new bacteria discovered in the Antarctic ten years ago, in order to verify the possibility of applications in healthcare, food processing and environmental rehabilitation.

30 May 2023

Researchers find oldest evidence of the plague in Britain to date

Researchers at the Francis Crick Institute have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date, reported in a paper published today in Nature Communications.

30 May 2023

Penn State researchers create first protein-based nano-computing agent

The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers.

26 May 2023

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

A new study published in the peer-reviewed OMICS: A Journal of Integrative Biology identified genes for virulence and antimicrobial resistance in two bacteria that co-occur with C. difficile, suggesting these pathogens as emerging potential threats in planetary health.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Exploring diverse ancestry is a critical factor in furthering medical research.

25 May 2023

Microplastics in the digestive tract of seabirds alters gut microbiome, finds study

Scientists have been worried about the potential harms of microplastics for years. These small plastic particles less than 5 mm in length have been found everywhere because of plastic pollution - from the Earth's deep oceans to remote regions in Antarctica, and even the seafood we eat. But, are microplastics really harmful?

25 May 2023

WHO chief: World must prepare for deadlier outbreak than COVID-19

The world should be prepared to respond to a disease outbreak of "even deadlier potential" than COVID-19, the head of the WHO said after the UN agency launched a global network to monitor disease threats.

23 May 2023

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

research paper presents a perspective on tackling the healthcare challenge of Alzheimer's disease (AD) by shifting focus to pre-dementia stages and advocating for personalized medicine through improved diagnosis, prediction, and prevention strategies, empowering patients to actively manage their health and delay the onset of dementia.

22 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Dad’s genome may be playing a bigger role in siblings born with ASD

Cold Spring Harbor Laboratory researchers have flipped the script on autism spectrum disorder (ASD) genetics.

22 May 2023

Opentrons Flex™ Lab Robot Launches to Accelerate Bioautomation Across Thousands of Life Science Experiments

Opentrons, a leader in lab automation, announces the launch of its Opentrons Flex robot, a new generation of affordable and easy-to-program liquid-handling lab robots designed to level the playing field for labs of all sizes and bring advanced lab automation to more researchers than ever before.

From Opentrons 22 May 2023

Unraveling the origins of humanity: New research challenges single-origin theory

Researchers explore the complex demographic history of Homo sapiens in Africa, revealing a reticulated population structure dating back to Marine Isotope Stage 5. The study challenges previous assumptions about archaic hominin contributions and emphasizes the significance of employing diverse models for robust inferences about ancient human history.

21 May 2023

Study finds socio-economic inequalities in access to novel therapies for many NSCLC patients

Novel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnosed with non-small cell lung cancer, according to a new study published in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer.

19 May 2023

Research findings bring order to the genomic chaos of ovarian high grade serous carcinoma

New research findings based on the evolution of malignant tumors increase our understanding of the characteristics of an ovarian cancer subtype that is difficult to treat.

19 May 2023

Genomics News and Research

Further Reading

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

CardioGen upgrade facilitates more accurate diagnosis of monogenic cardiovascular diseases

Researchers create an open-source, reproducible analysis platform for pediatric brain tumors

Computational approach could help pinpoint causal variants in the noncoding genome

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

Researchers find oldest evidence of the plague in Britain to date

Penn State researchers create first protein-based nano-computing agent

Two bacteria that co-occur with C. difficile as emerging potential threats in planetary health

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Microplastics in the digestive tract of seabirds alters gut microbiome, finds study

WHO chief: World must prepare for deadlier outbreak than COVID-19

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Dad’s genome may be playing a bigger role in siblings born with ASD

Opentrons Flex™ Lab Robot Launches to Accelerate Bioautomation Across Thousands of Life Science Experiments

Unraveling the origins of humanity: New research challenges single-origin theory

Study finds socio-economic inequalities in access to novel therapies for many NSCLC patients

Research findings bring order to the genomic chaos of ovarian high grade serous carcinoma

Omics eBook

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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