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Severe COVID-19 raises alarm for undiagnosed cancer

Severe SARS-CoV-2 infection is associated with a 1.31 higher risk of being diagnosed with cancer following hospital discharge, particularly renal, hematological, colon, and lung cancers, suggesting a potential link between the infection and undiagnosed cancer.

1 Jun 2023

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Novel EABR technology enhances potency and breadth of vaccine-induced responses through antigen presentation.

30 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Researchers highlighted the pace of development of COVID-19 therapies during the pandemic and the challenges that hinder the widespread availability of anticoronavirals.

8 May 2023

The dynamics and interactions between the skin metabolome, microbiome, and UV exposure

Researchers evaluated metabolic profile changes of the skin in relation to microbiota and UV exposure.

5 May 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

Immune cells in the duodenum may be responsible for iron absorption problems, study suggests

Approximately one to two milligrams of the trace element must be supplied daily through food and finally absorbed in the duodenum for a balanced iron metabolism.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

The association between neutralizing antibody response breadth and long COVID symptoms

Researchers assessed neutralizing antibody responses before and after severe acute respiratory syndrome coronavirus 2 Omicron.

5 Apr 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Menin protein protects against aging and cognitive decline

In a recent study published in the journal PLoS Biology, researchers from the University of Xiamen, China, explored the role of the hypothalamic menin in driving aging and associated cognitive decay.

23 Mar 2023

Study provides insights on stability of SARS-CoV-2 in biological fluids of animals

In a recent study published in the Viruses journal, researchers assessed the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among biological fluids found in animals.

21 Mar 2023

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

COVID-19 has caused significant global panic after its rapid emergence more than 3 years ago. Although we now have highly effective vaccines against the SARS-CoV-2 virus, which causes COVID-19, scientists continue to study emerging SARS-CoV-2 variants in order to safeguard public health and devise global preventive strategies against emerging variants.

20 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Study sheds new light on a key protein involved in the process of spermiation

In order to achieve good times in their races, many Olympic swimmers wear swimsuits that are low in water resistance.

13 Mar 2023

Evolutionary convergence of the SARS-CoV-2 A-lineage spike sequences

Researchers assessed the impact of evolutionary convergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) A-lineage (Clade 19B) spike sequences on B-lineage viral replication.

9 Mar 2023