Biochemistry

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St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Chemical found in widely used sweetener breaks up DNA

A new study finds a chemical formed when we digest a widely used sweetener is "genotoxic," meaning it breaks up DNA.

31 May 2023

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers from Japan fed isocaloric diets with varying amounts of protein to young and middle-aged male mice.

31 May 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

New hope for low-cost biological cleanup of industrial pollutants

University of California, Riverside, chemical and environmental engineering scientists have identified two species of bacteria found in soil that break down a class of stubborn "forever chemicals," giving hope for low-cost biological cleanup of industrial pollutants.

30 May 2023

Almond milk yogurt tops the list in a nutritional comparison of plant-based and dairy yogurts

In a nutritional comparison of plant-based and dairy yogurts, almond milk yogurt came out on top, according to research led by a University of Massachusetts Amherst food science major.

30 May 2023

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

A scientific collaboration between the University of São Paulo (USP) in Ribeirão Preto, Brazil, and Clemente Estable Institute of Biological Research (IIBCE) in Montevideo, Uruguay, is experimenting with two new bacteria discovered in the Antarctic ten years ago, in order to verify the possibility of applications in healthcare, food processing and environmental rehabilitation.

30 May 2023

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

30 May 2023

Using ex vivo gene therapy to fight obesity and diabetes in mice

A scientific team from the University of Barcelona and the CIBERobn has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease.

30 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Japanese natto consumption may help realize a healthy and longer-living society

Health is wealth as the saying goes and new research now shows that it is possible to have a healthy, less stressed society through familiar and inexpensive foods.

26 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Short-chain fatty acids play a beneficial role in the gut-lung axis of aging mice

The gut microbial community structure-; communities of bacteria, viruses and fungi that live in the intestines-; influences the inflammatory response in the lungs of aging mice, according to researchers from the Institute of Functional Anatomy at Charité, the Medical University of Berlin in Germany.

25 May 2023

Oxygen restriction associated with longer lifespan in lab mice

For the first time, researchers have shown that reduced oxygen intake, or "oxygen restriction", is associated with longer lifespan in lab mice, highlighting its anti-aging potential.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Biochemistry

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Peptidomimetic antibiotics may be effective against resistant bacteria

Chemical found in widely used sweetener breaks up DNA

Moderate-protein diet improves metabolic health in both young and middle-aged mice

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

New hope for low-cost biological cleanup of industrial pollutants

Almond milk yogurt tops the list in a nutritional comparison of plant-based and dairy yogurts

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

Using ex vivo gene therapy to fight obesity and diabetes in mice

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Japanese natto consumption may help realize a healthy and longer-living society

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Short-chain fatty acids play a beneficial role in the gut-lung axis of aging mice

Oxygen restriction associated with longer lifespan in lab mice

Looking at cancer drugs to help put the brakes on classic indicators of aging

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

Honokiol inhibits replication of SARS-CoV-2 in several cell types

Exploring how and why nitrate has contrasting potential risks and benefits

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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